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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YWHAQ
All Species:
13.64
Human Site:
S92
Identified Species:
25
UniProt:
P27348
Number Species:
12
Phosphosite Substitution
Charge Score:
0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27348
NP_006817.1
245
27764
S92
K
V
E
S
E
L
R
S
I
C
T
T
V
L
E
Chimpanzee
Pan troglodytes
XP_525684
416
45456
S263
K
V
E
S
E
L
R
S
I
C
T
T
V
L
E
Rhesus Macaque
Macaca mulatta
XP_001097635
245
27803
S92
K
V
E
S
E
L
R
S
I
C
T
T
V
L
E
Dog
Lupus familis
XP_856222
224
25254
L77
R
S
I
C
T
T
V
L
E
L
L
D
K
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQV8
246
28068
D94
K
I
E
A
E
L
Q
D
I
C
N
D
V
L
E
Rat
Rattus norvegicus
P63102
245
27753
D92
K
I
E
T
E
L
R
D
I
C
N
D
V
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518806
277
31320
D125
K
I
E
A
E
L
Q
D
I
C
N
D
V
L
E
Chicken
Gallus gallus
Q5ZMD1
245
27764
S92
K
V
E
S
E
L
R
S
I
C
T
T
V
L
E
Frog
Xenopus laevis
Q8AVQ3
244
27740
D92
K
V
E
T
E
L
Q
D
I
C
K
D
V
L
D
Zebra Danio
Brachydanio rerio
Q5PRD0
244
27628
E92
K
I
E
A
E
L
Q
E
I
C
N
D
V
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29310
248
28209
E95
R
V
E
K
E
L
R
E
I
C
Y
E
V
L
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20655
248
28049
D94
K
V
E
K
E
L
R
D
I
C
Q
D
V
L
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P34730
273
31043
K97
K
I
E
T
E
L
T
K
I
S
D
D
I
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.8
99.1
91.4
N.A.
80.4
80
N.A.
72.9
98.7
77.5
78.3
N.A.
76.6
N.A.
75.4
N.A.
Protein Similarity:
100
58.8
99.1
91.4
N.A.
90.6
91
N.A.
80.5
100
90.6
89.8
N.A.
85.8
N.A.
83.8
N.A.
P-Site Identity:
100
100
100
0
N.A.
60
60
N.A.
60
100
60
53.3
N.A.
60
N.A.
66.6
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
80
73.3
N.A.
80
100
80
73.3
N.A.
66.6
N.A.
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
56.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
71.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
24
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
85
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
39
0
0
8
62
0
0
8
% D
% Glu:
0
0
93
0
93
0
0
16
8
0
0
8
0
0
47
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
39
8
0
0
0
0
0
93
0
0
0
8
0
0
% I
% Lys:
85
0
0
16
0
0
0
8
0
0
8
0
8
0
0
% K
% Leu:
0
0
0
0
0
93
0
8
0
8
8
0
0
93
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
31
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
31
0
0
0
8
0
0
0
0
% Q
% Arg:
16
0
0
0
0
0
54
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
31
0
0
0
31
0
8
0
0
0
0
16
% S
% Thr:
0
0
0
24
8
8
8
0
0
0
31
31
0
0
0
% T
% Val:
0
54
0
0
0
0
8
0
0
0
0
0
85
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _